A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with the same mutation, a rare finding of a direct genetic link to psychosis, report researchers at the University of Illinois Urbana-Champaign and colleagues in Massachusetts and Germany.
The mutation increases levels of glycine decarboxylase, or GLDC, an enzyme responsible for regulating glycine in the brain. Glycine activates receptors for the neurotransmitter glutamate, called NDMA receptors.
"The genetics of schizophrenia is very complex, and it is rare that mutations found in patients can be...
Michelle Hammer is a schizophrenia activist and spends her time passionately fighting stigma. She is an NYC native featured in the WebMD documentary...
Summary: A new study has identified a distinct brain network connecting areas of atrophy associated with schizophrenia, offering a unified view of its...
