Summary: Researchers have uncovered shared biological mechanisms across major psychiatric disorders by analyzing postmortem brain samples from the dorsolateral prefrontal cortex. Instead of looking at gene expression broadly, they zoomed in on the exon level—the building blocks that influence how proteins are made.They found that gene activity differences were only apparent at this finer scale, not at the whole-gene level. The study revealed that disruptions in stress hormone regulation, dopamine signaling, and circadian rhythms are common to multiple disorders, including schizophrenia.Key Facts:Exon-Level Insights: Psychiatric patients showed differences from...
Summary: A new meta-analysis highlights a strong connection between early-onset neurodevelopmental disorders with linguistic symptoms and left- or mixed-handedness. Disorders like dyslexia, autism,...
Linguistic symptoms and an onset early in life: Disorders to which this applies are frequently associated with left-handedness resp. mixed-handedness.
The fact that left-handedness...
Depression, schizophrenia and other mental health conditions affect 1 in 4 people in their lifetime, but mechanisms underlying these conditions are poorly understood....
