A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with the same mutation, a rare finding of a direct genetic link to psychosis, report researchers at the University of Illinois Urbana-Champaign and colleagues in Massachusetts and Germany.
The mutation increases levels of glycine decarboxylase, or GLDC, an enzyme responsible for regulating glycine in the brain. Glycine activates receptors for the neurotransmitter glutamate, called NDMA receptors.
"The genetics of schizophrenia is very complex, and it is rare that mutations found in patients can be...
Can SMELL Really Detect SCHIZOPHRENIA Better Than Current Methods?
Anecdotal Evidence and Observations
Michelle Hammer, who has schizophrenia, initially dismissed the idea that people with...
Schizophrenia is a serious mental disorder that affects around 1% of the world's population. Researchers of the University of Barcelona have identified a...
Summary: People with schizophrenia experience impaired contrast perception, affecting their ability to differentiate light intensity and recognize shapes and textures. This deficit may...