A new study in the peer-reviewed Journal of Child and Adolescent Psychopharmacology estimated the incidence of neuroleptic malignant syndrome (NMS), a potentially fatal adverse effect of antipsychotic treatment, among individuals ages 5-24 years.Wayne Ray, PhD, from the Vanderbilt University School of Medicine, and coauthors, used national Medicaid data from 2004-2013 to identify patients beginning antipsychotic treatment and calculated the incidence of NMS during antipsychotic use. The investigators identified five factors that independently predicted increased NMS incidence: age 18-24...
Summary: A recent review of genetic and population studies reveals that premorbid cognitive deficits in schizophrenia, such as lower IQ, are largely due...
A study led by researchers at Tampere University has mapped genes linked to schizophrenia and uncovered a mechanism that disrupts synaptic plasticity in...
Summary: Researchers have identified a mechanism that impairs synaptic plasticity in individuals with schizophrenia, revealing the role of three key proteins. Using computational...