Cord blood transplants are known to tolerate genetic mismatches better than other donor sources. But one specific HLA pairing may sharply raise the risk of severe graft-versus-host disease.
Umbilical cord blood transplantation has expanded treatment options for patients with blood cancers and other life-threatening hematological disorders, especially when a fully matched donor cannot be found (1✔ ✔Trusted SourceHigh-Risk Human Leukocyte Antigen Mismatch Combinations Responsible for...