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Can we prevent Alzheimer’s before it begins? | WashU



Is an Alzheimer’s prevention possible? WashU researchers Jai Rudra and Meredith Jackrel are developing a groundbreaking immunotherapy that trains the immune system to clear amyloid deposits—the protein buildup driving Alzheimer’s disease. Unlike treatments that only manage symptoms, this approach uses engineered peptides to target the root cause of cognitive decline. Backed by a major National Institute on Aging grant, this research marks a shift toward Alzheimer’s prevention and long-term brain health.

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In this video: 0:00 – The challenge of managing Alzheimer’s symptoms 0:45 – How engineered peptides train the immune system 1:30 – Clearing amyloid deposits in the brain 2:15 – National Institute on Aging grant & future of prevention

#alzheimers #MedicalResearch #Immunotherapy #WashU #BrainHealth #ScienceNews @washuartsci @WashUEngineering

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About WashU
Washington University in St. Louis (WashU) is a nationally ranked, global leader in teaching, research and patient care. With a vibrant community of over 21,300 students and faculty from all 50 states and 100+ countries, WashU offers world-class programs across nine distinct schools, all anchored in purpose-driven scholarship and service to society. Discover how WashU brings us closer to the knowledge that changes lives and the stories that inspire us to change the world.

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